邱宪波

研究方向：

智能医学检测与创新仪器、微流控芯片与生化传感、光机电系统与POCT检测装置、生物医学信息处理与人工智能建模

Email:xbqiu@mail.buct.edu.cn

邱宪波，工学博士、教授、博士生导师，北京化工大学微流控芯片生物医学工程研究中心主任。美国宾夕法尼亚大学（UniversityofPennsylvania）博士后/研究助理（2006-2011），厦门大学副教授。从2002年至今，围绕“基础理论/方法创新-工程技术瓶颈突破-产业化应用”，主要从事：智能医学检测与创新仪器、微流控芯片与生化传感、光机电系统与POCT检测装置、生物医学信息处理与人工智能建模的基础及应用研究。在国际著名出版公司参与出版英文专著两章。在Sensorsand Actuators B: Chemical、Labon a Chip、Trendsin Analytical Chemistry、AnalyticaChimica Acta、Talanta等国内外知名期刊及会议发表论文100余篇，总引用2500余次。担任NatureBiomedicalEngineering等期刊审稿人。申请或授权发明专利70项（国际专利2项，美国专利6项，韩国专利2项，印度专利1项，非洲专利1项）。作为技术负责人或核心人员，先后成功研发了96孔荧光定量实时PCR仪、便携式血糖仪、便携式心脏起搏器无线程控仪、免疫荧光检测仪、免疫胶体金检测仪、全自动一体化HIV快速诊断微流控芯片系统（免疫/核酸）、微流控对流PCR核酸检测系统、一体化核酸自动提取微流控芯片系统、CD4+T淋巴细胞计数检测微流控芯片系统、离心式微流控芯片及仪器、等温扩增检测微流控芯片及仪器等，多项研究成果实现了产业化应用。曾获得上海市科技进步三等奖、上海市高校学生“创造发明三枪杯奖”、中国过程控制学会中国过程控制年会张钟俊青年优秀论文二等奖、中国仪器仪表学会中国信息获取与处理年会优秀论文一等奖，北京化工大学2020年度重要科技进展等各类奖励。承担国家自然科学基金（面上）、国家科技重大专项子课题、北京化工大学双一流重大建设项目、中央高校基本科研业务费项目、北京化工大学-中日友好医院生物医学转化工程研究中心联合基金项目、及若干企事业单位合作课题。

地址/联系方式

北京市朝阳区北三环东路15号，北京化工大学计算机楼（东）210室

Email:xbqiu@mail.buct.edu.cn

教学课程Teachingcourses

主要科研项目 ResearchProjects

主要成果、奖励Mainachievements

代表性论文 ResearchPaper                                 

[1]NanWang, Xiaobin Dong, Yijie Zhou, Rui Zhu, Luyao Liu, Lulu Zhangand XianboQiu*,A Low-Cost Handheld Centrifugal Microfluidic System for MultiplexedVisual Detection Based on Isothermal Amplification, Sensors, 2024,24, 5028

[2]LuyaoLiu, Lulu Zhang, Xueyu Zhang, Xiaobin Dong, Xiaodan Jiang, XiaoqiHuang, Wei Li, Xiaoming Xie, XianboQiu*,Analysis of cellular response to drugs with a microfluidicsingle-cell platform based on hyperspectral imaging, AnalyticaChimica Acta, 2024, 1288, 342158

[3]XiaobinDong, Zhiqian Tang, Xiaodan Jiang, Qiang Fu, Donglin Xu, LuluZhang, XianboQiu*,A highly sensitive, real-time centrifugal microfluidic chip formultiplexed detection based on isothermal amplification, Talanta,2024, 268, 125319

[4]QiangFu, Yunping Tu, Lun Cheng, Lulu Zhang, XianboQiu*,A fully-enclosed prototype ‘pen’ for rapid detection ofSARS-CoV-2 based on RT-RPA with dipstick assay at point-of-caretesting, Sensors and Actuators: B. Chemical, 2023, 383: 133531

[5]Guijun Miao, Xiaodan Jiang, Dianlong Yang, Qiang Fu, Lulu Zhang,Shengxiang Ge, Xiangzhong Ye, Ningshao Xia, Shizhi Qian, and XianboQiu*,A Hand-Held, Real-Time, AI-Assisted Capillary Convection PCR Systemfor Point-of-Care Diagnosis of African Swine Fever Virus, Sensors andActuators B: Chemical, 2022, 358, 131476,https://doi.org/10.1016/j.snb.2022.131476

[6]Luyao Liu, Xiaobin Dong, Yunping Tu, Guijun Miao, Zhongping Zhang,Lulu Zhang, Zewen Wei, Duli Yu1, and XianboQiu*,Methods and Platforms for Analysis of Nucleic Acids from Single-CellBased on Microfluidics, Microfluidics and Nanofluidics, 2021, 25:87,https://doi.org/10.1007/s10404-021-02485-0

[7]Xiaobin Dong, Luyao Liu, Yunping Tu, Jing Zhang, Guijun Miao, LuluZhang, Shengxiang Ge, Ningshao Xia, Duli Yu, XianboQiu*,Rapid PCR Powered by Microfluidics: A Quick Review Under theBackground of COVID-19 Pandemic, Trends in Analytical Chemistry,2021, 143, 116377

[8] XianboQiu*,Huiqin Jiang, Xiaolei Zhang, Ke Li, Shengxiang Ge, Ningshao Xia, andMichael G. Mauk, Plasma Separator with Multifunctional DeformableChamber Equipped with Porous Membrane for Point-of-Care Diagnostics,Analyst, 2020, 145, 6138 - 6147

[9]Guijun Miao, Lulu Zhang, Jing Zhang, Shengxiang Ge, Ningshao Xia,Shizhi Qian, Duli Yu, and XianboQiu*,Free convective PCR: From principle study to commercialapplications—A critical review, Analytica Chimica Acta, 2020,1108, 177-197 (封面文章)

[10] XianboQiu*,Shiyin Zhang, Fei Xiang, Di Wu, Meng Guo, Shengxiang Ge, Ke Li,Xiangzhong Ye, Ningshao Xia, and Shizhi Qian, Instrument-FreePoint-of-Care Molecular Diagnosis of H1N1 Based on MicrofluidicConvective PCR, Sensors and Actuators B: Chemical, 2017, 243, 738–744

[11]Huiqin Jiang, Di Wu, Liuwei Song, Quan Yuan, Shengxiang Ge, XiaopingMin, Ningshao Xia, Shizhi Qian, XianboQiu*,A Smartphone-Based Genotyping Method for Hepatitis B Virus atPoint-of-Care Settings, SLAS Technology. 2017, 22(2), 122-129 (the2018 SLAS Technology Ten: Translating Life SciencesInnovation, 入选SLAS2018十大热点文章,Jan. 24, 2018)

[12] XianboQiu*,Liuwei Song, Shuo Yang, Meng Guo, Quan Yuan, Shengxiang Ge, XiaopingMin, Ningshao Xia, A fast and low-cost genotyping method forhepatitis B virus based on pattern recognition in point-of-caresettings, Scientific Reports, 2016, 6: 28274

[13] XianboQiu,Changchun Liu, Michael G. Mauk, Robert W. Hart, Dafeng Chen, JingQiu, Terry Kientz, Jonathan Fiene, and Haim H. Bau*, A portableanalyzer for pouch-actuated, immunoassay cassettes, Sensors andActuators B: Chemical, 2011, 160(1), 1529-1535

[14]Changchun Liu, Michael G. Mauk, Robert Hart, XianboQiu,and Haim H. Bau*, A self-heating cartridge for molecular diagnostics,Lab on a Chip, 2011, 11(16), 2686-2692

[15]Changchun Liu, Eran Geva, Michael Mauk, XianboQiu,William R. Abrams, Daniel Malamud, Kelly Curtis, S. Michele Owen andHaim H. Bau*, An isothermal amplification reactor with an integratedisolation membrane for point-of-care detection of infectiousdiseases, Analyst, 2011, 136(10), 2069-2076

[16]Jitae Kim, Michael Mauk, Dafeng Chen, XianboQiu,Jungkyu Kim, Bruce Gale and Haim H. Bau*, A PCR reactor with anintegrated alumina membrane for nucleic acid isolation, Analyst,2010, 135(9), 2408-2414

[17] XianboQiu,Michael G. Mauk, Dafeng Chen, Changchun Liu and Haim H. Bau*, A largevolume, portable, real-time PCR reactor, Lab on a Chip, 2010, 10(22),3170–3177

[18]Dafeng Chen, Michael Mauk, XianboQiu,Changchun Liu, Jitae Kim, Sudhir Ramprasad, Serge Ongagna, William R.Abrams, Daniel Malamud, Paul L. A. M. Corstjens and Haim H. Bau*, Anintegrated microfluidic cassette for isolation, amplification, anddetection of nucleic acids, Biomedical Microdevices, 2010, 12(4),705-719

[19] XianboQiu,Jason A. Thompson, Zongyuan Chen, Changchun Liu, Dafeng Chen, SudhirRamprasad, Michael G. Mauk, Serge Ongagna, Cheryl Barber, William R.Abrams, Daniel Malamud, Paul L. A. M. Corstjens and Haim H. Bau*,Finger-actuated, self-contained immunoassay cassettes, BiomedicalMicrodevices, 2009, 11(6), 1175-1186

[20]Changchun Liu, XianboQiu,Serge Ongagna, Dafeng Chen, Zongyuan Chen, William R. Abrams, DanielMalamud, Paul L. A. M. Corstjens and Haim H. Bau*, A timer-actuatedimmunoassay cassette for detecting molecular markers in oral fluids,Lab on a Chip, 2009, 9(6), 768-776

专利、软件著作权

申请或授权发明专利70项（国际专利2项，美国专利6项，韩国专利2项，印度专利1项，非洲专利1项）；获批软件著作权10余项。

奖励

曾获得上海市科技进步三等奖、上海市发明协会上海市高校学生“创造发明三枪杯奖”、中国过程控制学会中国过程控制年会张钟俊青年优秀论文二等奖、中国仪器仪表学会中国信息获取与处理年会优秀论文一等奖、3rdClass Award of Conference Poster Contest, “Lab-on-a-chip forpoint-of-care nucleic acid based testing”, The Annual"Discovery to Commercialization Conference" of theNanotechnology Institute, Philadelphia, USA,2009、北京化工大学优秀班主任、北京化工大学2020年度重要科技进展等奖励。

研究成果Research Achievements